Deerfield Management was established in 1994 by Arnold Snider with an initial equity investment of $17 million. Snider brought significant experience to the firm, having worked as a pharmaceutical analyst at Kidder Peabody and later as a managing director at Tiger Management. Deerfield is considered one of the Tiger Cubs, a group of hedge funds founded by former employees of Tiger Management. In 2000, James Flynn joined Deerfield and eventually rose to the position of CEO. Snider officially retired from the firm in 2005.


In March 2019, Deerfield announced a strategic partnership with Harvard University aimed at funding drug development and medical treatments. Deerfield committed $100 million to this initiative, which was channeled through a newly formed entity called Lab1636. Continuing its focus on healthcare, Deerfield acquired Melinta Therapeutics in April 2020 by exchanging $140 million in secured debt for full equity ownership after Melinta filed for Chapter 11 bankruptcy protection.
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